

Wax anatomical models were first made by Gaetano Giulio Zummo (1656–1701) who first worked in Naples, then Florence, and finally Paris, where he was granted monopoly right by Louis XIV. Felice Fontana made cadaveric specimens into wax models by the casting method for anatomical teaching. This work so affected Pope Benedict XIV that he ordered construction of a museum of anatomy in Bologna In 1742, named Ercole Lelli and featuring anatomical wax models. The Tabulae anatomicae of Bartolomeo Eustachi ("Eustachius") (1552), printed in 1714, had a major effect on the history of anatomical wax models. Giulio Cesare Casseri ("Casserius"), Spighelius, and William Harvey are other followers of the pictures of Andreas Vesalius. By 1600 Fabricius had gathered 300 anatomical paintings and made an anatomical atlas named the Tabulae Pictae. The anatomical pictures of Vesalius were followed by those of Johann Vesling ("Veslingius") and Hieronymus Fabricius. These pictures greatly influenced the creation of future anatomical wax models. The book included drawings of human females and males with their skins dissected. In 1543 Vesalius wrote an anatomical masterwork named in Latin De humani corporis fabrica libri septem ("On the fabric of the human body in seven books"), or in short De Fabrica. At age 25 Vesalius realized that the anatomical knowledge of Galen was derived from animal anatomy and therefore Galen had never dissected a human body. Galen wrote that the bone of the arm is the longest bone in the human body, but Vesalius found that the bone of the thigh is actually the longest bone in human body. For example, Galen wrote that the sternum has seven segments, but Vesalius found it has three segments. He studied many details of human anatomy and found that Galen made some anatomical mistakes. When he moved to Italy and entered the University of Padua, he began dissecting human bodies. Andreas Vesalius (1514–1564), a Flemish anatomist, was at first a "Galenist" at the University of Paris.
